Sickle cell osteomyelltis of the mandible is not necessarily dentally relafed. Some report^^^,*^ indicate that blood alkalization aborts and prevents sickle cell crisis. Blood~ ~ ~~gas abnormalities should be quickly corrected, especially acidosis. The use of a hyperbaric oxygen chamber may aid in tissue oxygen p e r f ~ s i o n. An arterial line will assure a continuous mean arterial pressure observation indicating the tissue perfusion status. Arterial blood gas levels should be frequently determined during administration of general anesthesia. Possible complications include hepatitis, hemosiderosis, and the development of red blood cells isoantibodies? Therefore, good cooperation and communication with the hematology department are essential. Although exchanged transfusions raise the patient's normal hemoglobin level, they have inherent risks. Normal transfused cells cannot participate in the sickling phenomenon. Exchange transfusions of the patient's red blood cells with hemoglobin AA-packed red blood cells have been advocated for reducing general anesthesia risks.2,18,2',22 Normal hemoglobin levels should be restored to 70% to 80% because they augment the oxygen-carrying capacity and reduce the number of circulating sickle cells.
hours are recommended.'-21 A blanket warmer should be used during the surgery and the patient's temperature should be monitored. Mandibular osteomyelitis secondary to infarcts associated with sickle cell anemia Mandibular osteomyelitis secondary to infarcts associated with sickle cell anemia
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